New Release TachyNA™ Plasma cfNA Kit — Cat. No. H02CN1 — now shipping from Biomics Inc. Read the announcement →
NA-DP™ Platform Nucleic Acid Direct Pass Biomics Inc.

One membrane chemistry. Many ways to run it.

NA-DP™ membrane holds back proteins, lipids, and debris and lets nucleic acids pass straight through. Because nothing depends on capturing and releasing the DNA, the same membrane works in a spin column for the lab, a syringe for POCT, a plate for high throughput, or a preparative column for larger volume.

The TachyNA™ Kits are a series of nucleic acid purification products built based on NA-DP™ technology.

1 pass
Single-step extraction
4 formats
One chemistry
20bp–20kb
Fragment recovery range
Fig. 01 · One core, every format
NA-DP™MEMBRANE CORESPIN COLUMNSYRINGE · POCT96-WELL PLATEPREPARATIVE COLUMN
Same membrane, every housing. The spin column ships today as TachyNA™ H02CN1; the other formats are available to qualified customers on request.
§ 01 — The principle Biomics Direct Pass vs. traditional methods

Hold back the impurities. Let the nucleic acid through.

Most extraction chemistries capture the nucleic acid, wash it, then release it — and each step costs time and material, especially short fragments. Biomics' NA-DP™ Direct Pass technology inverts that logic: the membrane adsorbs proteins, lipids, pigments, and debris, and nucleic acids pass straight through in a single step.

Fig. 02 · Traditional methods vs. Biomics Direct Pass
Bind–wash–elute

Traditional cfDNA methods

Silica column · 4 steps
SAMPLE IN ↓ SILICA + WASH BUFFER WASTE DNA LOST ELUATE BIND WASH WASH ELUTE
  • Short fragments lost to waste during binding
  • Bound DNA lost in each wash
  • Four steps before you have eluate
Biomics Inc. · NA-DP™

Biomics Direct Pass

1 step
SAMPLE IN ↓ NA-DP™ BIOMICS ELUATE ✓ ALL SIZES ✓ SINGLE PASS
  • Impurities held on the membrane
  • Fragments of every length collected
  • One step, no chaotropic salts
cfDNA fragmentsProteins, lipids, pigments, debrisWash bufferSchematic — not to scale

One pass, not four steps

The sample crosses the membrane once. There's no bind, wash, or elute to time, and no chaotropic salts carried into your assay.

Nothing captured, nothing lost

The membrane holds impurities, not nucleic acid — so short fragments aren't lost during binding and yield isn't lost to washes.

Any force that moves liquid

Centrifuge, syringe, vacuum, or gravity flow: whatever pushes the sample through the membrane can run the chemistry. That is what makes it a platform.

§ 02 — Formats Same chemistry, different housings

Explore Our Formats

Pick the way your lab — or your instrument — moves liquid. The NA-DP™ membrane is the same in each format, from a benchtop spin column to a point-of-care syringe to a preparative column.

Fig. 03 · Format explorer
×g
Shipping · Cat. No. H02CN1

Spin column

The format the TachyNA™ Plasma cfNA Kit ships in. Load the sample, spin once in a standard benchtop centrifuge, and collect purified cfDNA in the tube below.

Driving force
Centrifugation
Where it fits
Research and translational labs; first-time evaluation
Kits
50 preps (H02CN1) · 20 preps (H02CN1-E)
PRESS
On request

Syringe unit

The membrane sits in a filter housing at the tip of a syringe. Pressing the plunger pushes the sample through — no centrifuge needed, which suits point-of-care settings.

Driving force
Hand pressure
Where it fits
Point-of-care testing (POCT); sites without a centrifuge
123456789101112ABCDEFGH SBS FORMAT · 96 WELLS
On request

96-well plate

The membrane in an SBS-format 96-well plate, for processing up to 96 samples in one run. Large-volume formats are also available for bigger inputs.

Driving force
Plate centrifuge or vacuum
Where it fits
High-throughput cores and cohort studies
NA-DP™
On request

Preparative column

A larger gravity- or low-pressure column that runs bigger plasma or serum inputs through the same NA-DP™ membrane — for preparative-scale nucleic-acid recovery beyond the spin-column volume.

Driving force
Gravity or low pressure
Where it fits
Large-volume inputs; preparative-scale purification
Fig. 04 · NA-DP™ kit familyPhoto
NA-DP Technology kit boxes in several sizes, with one box open showing spin columns, collection tubes, and a reagent bottle. Labeled For Research Use Only.
NA-DP™ Technology packaging across kit sizes. For Research Use Only.

What you can order today

The TachyNA™ Plasma cfNA Kit in the Spin Unit format: 50 preparations (Cat. No. H02CN1) or a 20-preparation evaluation kit (H02CN1-E).

Syringe, 96-well plate, and large-volume formats are supplied to qualified customers on request.

§ 03 — Fragment window Why short fragments survive

No capture step. No size cutoff.

Bind–wash–elute chemistries favor fragments long enough to bind well. NA-DP™ never has to capture the nucleic acid, so it isn't tuned to a size — short fragments, where much of the cfDNA signal sits, come through with everything else.

Scientist reviewing electropherogram and clustering plots on a monitor
Fig. 05 · Recovery across fragment lengthSchematic
SHORT-FRAGMENT ZONE ~167 bp PEAK RELATIVE ABUNDANCE 20501002005001k5k20k bp NA-DP™ SILICA
Schematic, not measured data. Typical plasma cfDNA size distribution on a log scale (fragment length, bp). Bars indicate relative recovery across size. For capillary-electrophoresis traces, see Evidence.
20 bp – 20 kb
Recovery range
3–6×
More 60-bp template vs. silica columns
<200, especially <90 bp
Excellent short-fragment recovery
qPCR · dPCR · NGS · NIPT
Plus methylation & fragmentomics

Comparative figures reflect Biomics internal head-to-head testing under matched conditions; full datasets available on request under NDA. For Research Use Only.

§ 04 — Roadmap One sample, four molecular layers

Nucleic acids today. Proteins, EVs, and cells next.

Biomics is building the sample-preparation layer for molecular diagnostics: three separation technologies designed to work from the same sample — NA-DP™ for nucleic acids, and wide-bore electrophoresis (WBE) for proteins, extracellular vesicles (EVs), and cells.

Fig. 06 · From one sample to four layers
ONE SAMPLENucleic acidsNA-DP™ · AVAILABLE NOWProteinsWBE · IN DEVELOPMENTExtracellularVesicles (EVs)WBE · IN DEVELOPMENTCellsWBE · IN DEVELOPMENTINTEGRATEDMULTI-OMIC &CLINICAL PROFILENUCLEIC ACIDPROTEINEVsCELLFROM ONE SAMPLEFINAL BIOINFORMATICS& CLINICAL INSIGHTSInteraction-awaregene / protein signatureCell-state phenotyping(incl. EV-mediated signal)Combined risk scoreActionable clinical data:· Screening & early detection· Therapy response· Recurrence / MRD· Risk stratificationInter-omics cross-talk
Solid teal lane: available now. Dashed lanes: in development. Diagram is conceptual and highlights multi-layer cross-talk.

Nucleic acids

Available now
NA-DP™ · Nucleic Acid Direct Pass

Cell-free DNA from plasma and serum today, with the TachyNA™ Plasma cfNA Kit. Cell-free RNA is on the roadmap.

Proteins

In development
WBE · Wide-Bore Electrophoresis

Electrophoretic protein separation from the same sample, built on Biomics' wide-bore electrophoresis heritage.

Extracellular Vesicles (EVs)

In development
WBE · vesicle separation

Wide-bore electrophoresis applied to isolating extracellular vesicles from the same sample, capturing EV-borne cargo alongside nucleic acids, proteins, and cells.

Cells

In development
WBE cell separation

Wide-bore electrophoresis applied to separating cell populations, so cells can be prepared alongside nucleic acids and proteins.

2001

Since its founding, Biomics has worked in three disciplines: sorbent design, membrane chemistry, and electrokinetic transport. NA-DP™ draws on the first two; WBE on the third. The platform is where twenty-five years of separation science converge on diagnostics.

§ 05 — Build on NA-DP™ Kits · OEM · co-development
Two scientists in lab coats discussing results in a laboratory Partner with us

Put NA-DP™ inside your workflow or instrument.

Use it as a finished kit, integrate the membrane into your own cartridge, or co-develop chemistry for a new sample type. We start with RUO and will be working towards IVD and support partners from RUO through LDT to IVD with proper products.

FINISHED KITSTachyNA™ H02CN1
OEMMembranes · cartridges
CO-DEVELOPMENTMatrix-tuned chemistry
REGULATORY PATHRUO → LDT → IVD